Translational Treatments: Advances in Renal Transplantation

Where: The Dobbs University Center (DUC), Emory University, 605 Asbury Circle, Winship Ballroom – 3rd Floor, Atlanta, GA 30322.
When: Thursday, November 3, from 8:00 a.m. to 4:00 p.m.


A one-day symposium on the latest research in kidney transplant was organized with doctors from Necker, Nantes, Toulouse and Emory Hospitals.
The Emory Transplant Center at Emory University hosted French and American immunologists and transplant physicians who addressed critical topics in the care of renal transplant patients in a one day conference. Distinguished research scholars gave presentations, shared ideas, and compared the best practices in the diagnosis and management of patients with kidney failure being treated with transplantation. Emerging needs in the field were defined and plans developed on the optimal research approaches to address these challenges.

PROGRAM OF THE SYMPOSIUM

8:00 a.m.: Welcome Talk
Dr. Christian P. Larsen, Joseph Brown Whitehead Professor and Chairman, Department of Surgery, Emory University School of Medicine and Pascal Le Deunff, Consul General of the Consulate General of France in Atlanta.

8:15 a.m.: Session I: Current Status of Costimulation Blockade in Transplantation
Moderator: Dr. Thomas C. Pearson

- Adhesion Molecule Blockade: A Potential Adjunct to Co-stimulation Blockade
Dr. William Kitchens

- Costimulation Blockade: Prospects for New Agents
Dr. Andrew Adams

- Costimulation and Adhesion Blockade in Clinical Islet Transplantation
Dr. Nicole Turgeon

- Selective CD 28 blockade, from the test tube to the primate
Dr. Bernard Vanhove


10:00 a.m.: Session II: Monitoring Immunosuppression: Biomarkers
Moderator: Dr. Allan D. Kirk

- Viral Infection as a Biomarker for Immunosuppression
Dr. Aneesh Mehta

- An Update on the ITN Tolerance Registry
Dr. Kenneth Newell

- Alloantibody in Liver Transplantation
Dr. Stuart Knechtle

- Long-term viral monitoring on belatacept-treated patients: the Toulouse experience
Dr. Lionel Rostaing

- Clinical and Biological biomarkers of operational tolerance
Dr. Jean-Paul Soulillou


Noon: Lunch and Round Table Discussion: Clinical Issues with the use of belatacept

- Induction Agent of Choice

- Treatment of rejection

- Belatacept failure: convert to which agents?

- Conversion from CNI to belatacept: who and when?


1:00 p.m.: Session III: Donor specific antibody: detection and management
Moderator: Dr. Howard Gebel

- The Current Status DSA Detection: Sensitivity and Clinical Relevance
Dr. Robert Bray

- Advanced Detection of Antibody Secreting and Memory B cells
Dr. Neal Iwakoshi

- HLA Immunization Impact on B Cells Subsets
Dr. Renaud Snanoudj

- Subclinical Antibody-Mediated Rejection
Dr. Christophe Legendre


2:30 p.m.: Session IV: Emergent Viral Infections in Renal Transplantation
Moderator: Dr. Antonio Guasch

- Emerging Viral infections: implications for Transplantation
Dr. Marshall Lyon

-  The Two Faces of Sirolimus: Viral- vs. Allo-Immunity
Dr. Mandy Ford

- Hepatitis E virus : a new emerging hepatotropic virus in organ transplant recipients
Dr. Nassim Kamar

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Contact : Jacqueline Signorini, Scientific Attaché, attache-univ.mst@ambascience-usa.org

For more information about France-USA scientific cooperation, see France-science.org

With the support of: